Adnofagia File

It is highly likely that the term is often confused with Adenophobia.

Oral-cervicofacial actinomycosis, caused by Actinomyces bacteria, can produce chronic, indurated masses that mimic tumors. Abscesses may drain through sinuses and, in very rare cases, extend into the pharynx. Colloquially, this has no relation to “adnofagia,” but the phonetic similarity to “actinophagia” (not a real term) might cause confusion. adnofagia

Adnofagia (from Latin adeps – fat, and Greek nodos – knot/swelling, plus phagein – to eat) is a recently proposed, still-controversial syndrome characterized by the progressive autophagocytic destruction of specialized adipose tissue surrounding lymph nodes. Unlike known lipodystrophies or lymphadenopathies, adnofagia specifically targets the perinodal adipocytes – fat cells that regulate lymphatic drainage and local immune function. Patients present with a paradoxical combination of regional lipoatrophy (fat loss), chronic low-grade lymphadenitis (swollen painful nodes), and systemic metabolic dysregulation. It is highly likely that the term is

First described in a 2018 case series from northern Scandinavia, the condition has since been identified (often retrospectively) in approximately 0.7% of patients with unexplained focal fat loss and persistent lymphadenopathy. This article reviews the proposed etiology, clinical presentation, histopathology, and emerging management strategies for adnofagia. Colloquially, this has no relation to “adnofagia,” but

In cases where no nutritional deficiency is found, the cause may be psychological.