Meyd-873 May 2026

By Dr. Alex Rivera, Ph.D. – Molecular Pharmacology & Drug Discovery
April 4 2026


Stay tuned as we move forward—MEYD‑873 could change the standard of care for KRAS‑driven solid tumors. MEYD-873

— Dr. Maya Patel, Head of Translational Oncology, NovaCure Therapeutics Stay tuned as we move forward— MEYD‑873 could

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    | Question | Answer | |----------|--------| | Is MEYD‑873 a cure? | Not yet. It is a disease‑modifying therapy that aims to extend survival and improve quality of life. | | Who can enroll in the trial? | Adults (≥ 18 y) with confirmed KRAS‑G12D mutation and a RAF‑DimerScore ≥ 2, who have progressed after standard therapy. | | What are the most common side effects observed so far? | Mild nausea, transient fatigue, and occasional Grade 1–2 elevation of alkaline phosphatase—all manageable with standard supportive care. | | When will the drug be available? | If Phase 3 confirms efficacy, we anticipate a 2029 US launch (subject to regulatory approval). | | How does the companion diagnostic work? | A single‑plex NGS assay for KRAS‑G12D plus a validated IHC stain for RAF‑dimer activity; results are returned within 7 days. |