V2.0: Pktool

The PKTool configuration file, pktool.conf, allows users to customize the tool's behavior. The file format is as follows:

[repository]
list=repositories
[package]
install-recommends=true

This configuration file specifies a list of repositories and enables the installation of recommended packages.

There are two primary tools that the name PKTool v2.0 commonly refers to: a specialized pharmaceutical modeling tool for drug discovery and a general-purpose Excel utility suite. 1. BMGF / MMV PKTool v2.0 (Pharmacokinetics)

This version of PKTool is a free modeling software developed to assist the Global Health community in drug discovery and development. It is often highlighted in webinars hosted by Medicines for Malaria Venture (MMV).

Primary Function: Predicting human pharmacokinetics (PK) and dosing from preclinical animal and in vitro data. pktool v2.0

Key Methodology: Uses allometric scaling principles, specifically single-species allometry, to project parameters like clearance ( CLcap C cap L ), volume of distribution ( ), and absorption rate ( ) to human scales.

v2.0 Improvements: The 2.0 update added features to analyze long-acting or extended-release formulations, addressing specific feedback from the Global Health community. Technical Details: Allometry: Fixed exponents are typically used for scaling ( for clearance; for volume and

Inputs: Requires data such as plasma protein binding, microsomal/hepatocyte clearance, and animal PK parameters. 2. PK's Utility Tool v2.0 (Excel Add-in)

This version refers to a productivity suite for Microsoft Excel created by "PK: An Excel Expert." It is designed to extend standard Excel functionality with custom formulas. The PKTool configuration file, pktool

Purpose: A collection of user-defined functions (UDFs) to automate data cleaning and extraction tasks. Key Features:

PK_Get_Emails: Automatically extracts email addresses from long strings of text.

PK_Get_Distance: Calculates the distance in kilometers between two geographic points using latitude and longitude.

Data Analysis: Includes functions for unique value counts (PK_Unique_Count), duplicate counts, and advanced lookups based on cell background color. This configuration file specifies a list of repositories

Availability: Offered as a free download to simplify complex data manipulation for non-technical users.

Note on "Apktool": If you are looking for information on "Apktool" (a tool for reverse engineering Android apps), version 2.0 was a significant milestone released around 2015 that introduced better support for modern Android resource structures and updated the internal smali library.

Which of these specific PKTools were you interested in learning more about? Global health compound design webinars

PKTool v2.0 provides efficient package installation and update mechanisms. Users can install packages from local repositories or remote sources, and the tool handles dependencies automatically. The update feature ensures that installed packages are kept up-to-date with the latest security patches and feature enhancements.

pktool capture -i eth0 -f "tcp port 443" -o capture.pcap
pktool capture --timeout 10 --count 1000

Options: