Wilms Tumor Ppt New May 2026

Include a 2-minute case to engage your audience:

3-year-old girl with right renal mass. CT shows tumor thrombus in IVC below diaphragm. No metastases. Biopsy shows favorable histology. Molecular panel: 1q gain. How do you treat? wilms tumor ppt new

Answer per new guidelines: Stage III (tumor thrombus) + molecular high-risk → intensify to Regimen DD-4A + flank radiation (19.8 Gy) despite favorable histology. Include a 2-minute case to engage your audience:

| Type | Favorable (FH) | Unfavorable (UH) | |------|----------------|------------------| | Triphasic (blastema, stroma, epithelium) | Anaplasia (focal or diffuse) | | Prognosis >90% survival | Requires intensified chemo | 3-year-old girl with right renal mass

Incidence: ~500 new cases/year in the US; ~7% of all childhood cancers.

Bilateral: 5–10% (often with genetic syndromes).

Eponym: Named after Dr. Max Wilms (German surgeon, 1899).